Is your concerned depression is not responding to treatment? You're not alone. Clinical depression can sometimes be difficult to treat. When a person has tried multiple types of treatment options to treat their depression over the course of months or even years, professionals may refer to it as Treatment Resistant Depression (TRD).

Treatment Resistant Depression is simply an episode of depression that resists typical treatments, such as psychotherapy or medications. Studies report that as many as three out of every 10 patients in primary care with depression do not respond to any of the treatment options they've tried.* These men and women may have tried a variety of options, including different types of antidepressants, a combination of medications containing an antidepressant and an antipsychotic, multiple types of psychotherapy, and other approaches. Yet no treatment seems to work to ease their depression. Additionally, of the 40% who do respond to the first antidepressant they use, one out of every five has to stop taking it because of side effects.**

Prevalence of TRD

• Up to 35% of patients with Major Depressive Disorder (MDD) may have treatment-resistant depression.*
• Treatment-resistant depression (TRD) is defined as the failure of an episode of major depression to respond fully to a treatment that is known to be effective.
  
• The severity of TRD ranges from one failed episode of treatment to multiple failed episodes.

Qualified adults, age 18 and older that participate in this research study will receive monetary compensation, study-related medical evaluations, psychological assessments and investigational study drug at no cost.

If you would like to see if you may qualify to participate in this clinical study regarding Treatment Resistant Depression (TRD), please fill out our optional self-assessment questionnaire to the right or for more information please call (877) 453-0404.